The English abbreviation for calcium channel blockers is CCBs. CCBs are a class of drugs that effectively block the entry of calcium ions into the smooth muscle cells of blood vessels and the heart. They are commonly used to treat high blood pressure (hypertension), angina, and certain heart rhythm disorders.
They work by relaxing and widening the blood vessels, which helps to lower blood pressure, improve blood flow, and reduce the workload on the heart. By blocking the entry of calcium ions, CCBs prevent the contraction of smooth muscle in the blood vessels, resulting in their relaxation and decreased resistance to blood flow. This, in turn, leads to decreased blood pressure.
Some commonly prescribed CCBs include amlodipine, nifedipine, diltiazem, and verapamil. It is important to note that CCBs may have different effects on different types of calcium channels and may be further classified into dihydropyridines and non-dihydropyridines based on their selectivity towards certain calcium channels.
Overall, CCBs are an important class of medications used to manage various cardiovascular conditions by interfering with the influx of calcium ions into smooth muscle cells. They are effective in lowering blood pressure, relieving chest pain, and improving overall heart function.